Immune Modulation of Pain and Addiction for Comprehensive Therapeutics
Our research follows a few central themes:
Immune system modulation of pain
- It is now accepted that the immune system plays a primary role in the experience and development of chronic pain. We are currently investigating the nature of this role and ways in which the immune system can be altered to alleviate chronic inflammatory and neuropathic pain through the use of genetic, pharmacological and behavioral interventions.
Immune system modulation of addiction
- Drugs of abuse elicit an immune response in the body and within the brain. We are currently investigating how changing the functioning of the immune system and the inflammatory processes alters the reinforcing value of classical drugs of abuse in rodent models of addiction.